职称 副教授

政治面貌 九三学社社员

学位 博士

邮箱 txy7933@163.com

研究方向 水产动物营养生理、代谢调控及饲料配方

 

 

教育经历 

1998.9-2002.6:广东海洋大学海燕策略官网，学士

2002.9-2005.6：中山大学生命科学学院，硕士

2008.9-2012.6：海燕策略官网，博士（在职）

主要职历 

2005.7-至今，海燕策略官网任教，先后任讲师（-2013）和副教授（2014-）

2012.6-2013.6：英国 University of St Andrews. Visiting Scholar

2015.7-2016.7：美国Cornell University, visiting associate professor  

科研成果 

1. 主持和参与的课题： 

（1）国家自然科学基金面上项目：32172983，黄颡鱼固醇调节元件结合蛋白-1（SREBP1）的SUMO化修饰机制及在脂类代谢中的作用机理，2022-2025，58万元，主持。

（2）湖北省高等学校优秀中青年科技创新团队计划，T201933，水产动物分子营养创新团队。参与。

（3）国家重点研发计划“蓝色粮仓科技创新”重点专项：2018YFD0900400，水产动物精准营养及其代谢调控机制，2018/12-2022/12, 4015万元，在研，参加。

（4）国家自然科学基金面上项目：31572605，JAK-STAT信号通路在瘦素（leptin）影响黄颡鱼卵巢发育中的作用及其分子机制。起止年月：2016-2019。61万元，主持。

（5）教育部留学回国人员课题：黄颡鱼JAK-STAT通路关键基因的分子特征及功能解析。起止年月：2015-2016。3万元，主持。

（6）国家自然科学基金青年科学基金：31001101，瘦素（leptin）对黄颡鱼卵巢发育的影响及机理。起止年月：2011-2013，19万元。主持。

2. 以第一和通讯作者发表论文39篇，其中SCI源刊论文28篇("*"示通讯作者），分别如下： 

2022

39. Xu, Y.C., Liu, G.H., Xu, Y.H., Zhao, T., Zheng, H., Tan, X.Y.*, 2022. Physiological and transcriptomic analyses reveal the toxicological mechanism and risk assessment of environmentally-relevant waterborne tetracycline exposure on the gills of tilapia (Oreochromis niloticus). Sci Total Environ, 806, 151290.

38. 谌芳， 仲崇超， 陈姝为，张电光，吕武宏，谭肖英*, 2022. 黄颡鱼溶酶体酸性脂肪酶基因的cDNA序列、启动子及其转录调控分析。水生生物学报，46, 98-105。

37. 郑华，徐一闯，赵涛，吕武宏，余岸艮，何杨，谭肖英*，2022。黄颡鱼STAT3乙酰化位点验证及其与SIRTs去乙酰化酶的关系。水产学报，46，173-182。

 

2021

36. Chen F, Zhong CC, Song CC, Chen SW, He Y, Tan XY*, 2021. Molecular characterization and functional analysis of two seteoidogenic genes TSPO and SMAD4 in yellow catfish. Int J Mol Sci, 22, 4505.

35. Lv WH, Chen GH, Zhuo MQ, Xu YH, Xu YC, Tan XY*, 2021. Functional analysis of steroidogenic factor 1 (sf-1) and 17α-hydroxylase/lyase (cyp17α) promoters in yellow catfish Pelteobagrus fulvidraco. Int J Mol Sci, 22, 195.

34. Tai Z, Ling S, Cheng J, Tan X*, 2021. Identification of three members of the Bmp family from yellow catfish Pelteobagrus fulvidraco and their transcriptional responses to a high fat diet. Aquaculture and Fisheries, 6, 63-68.

2020

33. Yang SB, Zhao T, Wu LX, Xu YC, Tan XY*, 2020. Effects of dietary carbohydrate sources on lipid metabolism and SUMOylation modification in the liver tissues of yellow catfish. Br. J. Nutr., 124, 1241-1250.

32. 崔恒阳，张电光，凌仕诚，陈光辉，谭肖英*，2020。饲料硒含量对黄颡鱼肠系膜脂肪组织中脂类代谢和miRNAs表达水平的影响。水生生物学报，44, 685-692。

31. 叶汉梅，魏晓雷，谭肖英*，2020。黄颡鱼细胞因子信号传导抑制因子SOCS1的原核表达及多克隆抗体制备。水产学报，44，523-527。

2019

30. 邰志鹏，徐异桓，张电光，谭肖英*，2019。黄颡鱼bmp2a与bmp4基因启动子的克隆及分析。海燕策略官网学报，38，91-96，

29. Ye HM, Zhao T, Wu LX, Cheng J, Tan XY*, 2019. Molecular characterization of nine suppressors of cytokine signaling (SOCS) genes from yellow catfish Pelteobagrus fulvidraco and their changes in mRNA expression to dietary carbohydrate levels. Fish Shellfish Immunol, 86, 906-912.

2018

28. Tai ZP, Li DD, Ling SC, Zhang DG, Cui HY, Tan XY*, 2018. Identification of full-length cDNA sequences for three development-relevant genes from female yellow catfish Pelteobagrus fulvidraco and their transcriptional responses to high fat diet. Comp Biochem Physiol, Part B, 225, 67-74.

27. Wu K, Tan XY*, Xu YH, Chen GH, Zhuo MQ, 2018. Functional analysis of promoters of genes in lipid metabolism and their transcriptional response to STAT3 under leptin signals. Genes, 9, 334; doi:10.3390/genes9070334.

26. Song YF, Tan XY*, Pan YX, Zhang LH, Chen QL, 2018. Fatty acid ß-oxidation is essential in leptin-mediated oocytes maturation of yellow catfish Pelteobagrus fulvidraco. Int. J. Mol. Sci., 19, 1457, doi:10.3390/ijms19051457.

25. You WJ, Tan XY*, Chen GH, Wei CC, Li DD, 2018. PPARß in yellow catfish Pelteobagrus fulvidraco: molecular characterization, tissue expression and transcriptional regulation by dietary Cu and Zn. Fish Physiol. Biochem., 44, 693-702.

2017

24. You WJ, Fan YF, Xu YH, Wu K, Tan XY*, 2017. Molecular characterization and functional analysis of PPARα promoter in yellow catfish Pelteobagrus fulvidraco. Gene, 627, 106-113.

23. Wu K, Tan XY*, Xu YH, Shi X, Fan YF, Li DD, Liu X, 2017. JAK family members: molecular cloning, expression profiles and their roles in leptin influencing lipid metabolism in Synechogobius hasta. Comp Biochem Physiol, 203, 122-131.

2016

22. Wu K, Tan XY*, Wei CC, You WJ, Zhuo MQ, Song YF, 2016. Isolation and expression analysis of STAT members from Synechogobius hasta and their roles in leptin affecting lipid metabolism. Int J Mol Sci, 17, 406; doi:10.3390/ijms17030406.

21. Wu K, Tan XY*, Xu YH, Chen QL, Pan YX, 2016. JAK and STAT members of Pelteobagrus fulvidraco and their roles in leptin affecting lipid metabolism. Gen Comp Endocrinol, 226, 14-26. 

20. Huang C, Tan XY*, Wu K, Chen QL, Zhuo MQ, Pan YX, Song YF, 2016. Osteological development and anomalies in larval stage of hatchery-reared yellow catfish Pelteobagrus fulvidraco. Aquacult Res, 47, 1125-1140.

2015

19. Zhang LH, Tan XY*, Wu K, Zhuo MQ, Song YF, Chen QL, 2015. Regulation and mechanism of leptin on lipid metabolism in ovarian follicle cells from yellow catfish Pelteobagrus fulvidraco. Gen Comp Endocrinol, 222, 116-123.

18. Song YF, Wu K, Tan XY*, Zhang LH, Zhuo MQ, Pan YX, Chen QL, 2015. Effects of recombinant leptin administration on hepatic lipid metabolism in yellow catfish Pelteobagrus fulvidraco: in vivo and in vitro studies. Gen Comp Endocrinol, 212, 92-99.

17. Zhuo MQ, Luo Z, Tan XY*, Hu W, Sun L, Zheng J, Chen Q., 2015. Purification and kinetic characteristics of hepatic 6-phosphogluconate dehydrogenase (6PGD) from yellow catfish Pelteobagrus fulvidraco. Turk J Biochem, 40, 15-23.

2014

16. Chen QL, Luo Z*, Tan XY*, Pan YX, Zheng JL, Zou M, 2014. Molecular cloning and mRNA tissue expression of thyroid hormone receptors in yellow catfish Pelteobagrus fulvidraco and Javelin goby Synechogobius hasta. Gene, 536, 232-237

15. Tan XY, Luo Z, Zhao YH, Liu CX, Liu X, 2014. Conjugated linoleic acid affects growth performance, hepatic fatty acid profile and lipid metabolism in juvenile Synechogobius hasta. Aquacult Nutr, 20, 143-152.

14. 卓梅琴，谭肖英*, 黄超，胡伟，朱庆玲，2014。黄颡鱼肝脏胞质中NADP依赖性的异柠檬酸脱氢酶(IDPc)的分离纯化和酶学性质。水产学报，38, 121-129.

13. Zhu QL, Luo Z, Zhuo MQ, Tan XY*, Sun LD, Zheng JL, Chen QL, 2014. In vitro exposure to copper influences lipid metabolism in hepatocytes from grass carp (Ctenopharyngodon idellus). Fish Physiol Biochem, 40, 595-605.

2013

12. Tan XY, Luo Z, Zeng Q, Zhao YH, Liu X, 2013. trans-10, cis-12 conjugated linoleic acid improved growth performance, reduced lipid deposition and influenced CPT I kinetic constants of juvenile Synechogobius hasta. Lipids, 48, 505-512

11.Gong Y, Luo Z, Zhu QL, Zheng JL, Tan XY*, Chen QL, Lin YC, Lu RH, 2013. Characterization and tissue distribution of leptin, leptin receptor and leptin receptor overlapping transcript genes in yellow catfish. Gen Comp Endocrinol, 182, 1-6.

10. Zheng JL, Luo Z, Zhu QL, Tan XY*, Chen QL, Sun LD, Hu W, 2013. Molecular cloning and expression pattern of 11 genes involved in lipid metabolism in yellow catfish Pelteobagrus fulvidraco. Gene, 531, 53-63.

2012

9. Tan XY, Xie P, Luo Z, Lin HZ, Zhao YH, Xi WQ, 2012. Dietary manganese requirement of juvenile yellow catfish, and effects on whole body mineral composition and hepatic intermediary metabolism. Aquaculture, 326-329, 68-73.

2011

8. Tan XY, Luo Z, Liu X, Xie CX, 2011. Dietary copper requirement of juvenile yellow catfish. Aquaculture Nutrition, 17, 170-176

2010

7. Tan XY, Luo Z, Zhang GY, Liu XJ, Jiang M, 2010. Effect of dietary cadmium level on the growth, body composition and several hepatic enzymatic activities of juvenile yellow catfish. Aquaculture Research, 41, 1022-1029

6. Tan XY, Luo Z, Xie P, Li XD, Liu XJ, Xi WQ, 2010. Effect of dietary conjugated linoleic acid on growth performance, body composition and hepatic intermediary metabolism in juvenile yellow catfish Pelteobagrus fulvidraco. Aquaculture, 310, 186-191.

2009

5. Tan XY, Luo Z, Xie P, Liu X, 2009. Effect of dietary linolenic acid/linoleic acid ratio on growth performance, hepatic fatty acid profiles and intermediary metabolism of juvenile yellow catfish. Aquaculture, 296, 96-101

4. 谭肖英，罗智，王卫民，熊邦喜，袁永超，樊启学，2009。饥饿对小规格斑点叉尾鮰体重及鱼体生化组成的影响。水生生物学报，33, 39-45

3. 谭肖英，罗智，李晓东，张世亮，孙忠正，2009。用螺旋藻替代鱼粉对仿刺参生长及其体组成的影响。大连海燕策略官网学报，24, 559-562

2007

2. 谭肖英，李晓东，罗智，袁闯，席文秋，刘胥，2007。矛尾复虾虎鱼繁殖前营养组成的研究。大连海燕策略官网学报，22, 306-310

2005

1. 谭肖英，刘永坚，田丽霞等，2005。饲料中碳水化合物水平对大口黑鲈生长、鱼体营养成分组成的影响。中山大学学报（自然科学版），44（增刊）, 258-263